mitPower is a tool that allows estimating the statistical power
in casecontrol association disease studies. Several utilities are
available such as: (i) a posteriori estimation of the statistical power,
(ii) sample size needed in order to reach a given statistical power, and
(iii) the estimation of the minimum deviation from the null hypothesis
(of no association) detectable under a given statistical power
(expressed as OR and haplogroup frequency in cases). It also allows
two different calibration procedures, asymptotic and permutation.
Note that mitPower is a generalized model that work with 2 x k tables;
therefore, it can be used with uniparental data (Ychromosome, mtDNA;
either haplogroups or SNPs) or with autosomal diploid data (e.g. autosomal SNPs).
More information: FAQ


