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mitPower
Mitochodrial DNA Case-Control Association
Studies. Estimation of the Statistical Power |
| mitPower is a tool that allows estimating the statistical power in case-control association disease studies. Several utilities are available such as: (i) a posteriori estimation of the statistical power, (ii) sample size needed in order to reach a given statistical power, and (iii) the estimation of the minimum deviation from the null hypothesis (of no association) detectable under a given statistical power (expressed as OR and haplogroup frequency in cases). It also allows two different calibration procedures, asymptotic and permutation. Note that mitPower is a generalized model that work with 2 x k tables; therefore, it can be used with uniparental data (Y-chromosome, mtDNA; either haplogroups or SNPs) or with autosomal diploid data (e.g. autosomal SNPs). More information: FAQ |
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